BC / ADBCE / CE

c. 541 CE–c. 544 CE

First documented Justinianic plague outbreak

Roman Empire · Salud, población y administración

Late Antique sources record a plague outbreak between 541 and 544 in territories of the eastern empire. Biomolecular evidence supports identification with Yersinia pestis, but its mortality, reach, and historical weight remain debated.

Precision, calendar, and review
Start
year · approximate
End
year · approximate
Calendar and convention
Historical-era years; the source calendar is not identified. No conversion of days is assumed.
Year zero
The scale goes from 1 BCE to 1 CE without year zero. Changing era names changes labels only.
Documentary review
Date not recorded

Reading the date: duration of a process.

Sources

  1. pmc.ncbi.nlm.nih.gov (opens in a new tab)
    Source provenance and scope
    Publication date
    Pending verification: the source could not be accessed
    Bibliographic date checked
    2026-09-23

    The correspondence between this reference and individual claims has not yet been itemized.

This record is an editorial synthesis. Consult the sources to check claims and their limits. Chronological relationships alone do not establish causation.

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